Hanna Jaaro-Peled

This study shows that astrocyte redox imbalance causes neuronal hypoactivity and affective behaviors in epilepsy, distinct from seizure mechanisms.

This study identifies nuclear GAPDH translocation as a mediator of stress-induced cardiac hypertrophy through BRG1-associated chromatin remodeling in mice and human patients.

This study identifies the miR-124-AMPAR pathway as a common mediator linking polygenic risks to shared behavioral changes in schizophrenia and bipolar disorder.

This study shows that the cortico-striatal circuit regulates sensorimotor gating through Disc1/Huntingtin-mediated Bdnf transport, with lithium restoring deficits in Disc1-LI mice.

This study shows that Disc1 deficiency in mice reduces inhibitory drive in the medial prefrontal cortex, linked to impaired feedforward inhibition in the MD-mPFC circuit.