Brenda R. S. Temple

PHENOMS: Open-Source Software for Rust-Accelerated Hydrogen-Bond Analysis in Molecular Dynamics Simulations

PHENOMS analyzes hydrogen-bond networks in molecular dynamics simulations using Rust-accelerated code, achieving significant speedup over Python-based tools and demonstrating its utility with HDX-MS data.

Coro1A and TRIM67 collaborate in netrin-dependent neuronal morphogenesis

This study identifies Coro1A and TRIM67 as collaborators in netrin-dependent neuronal morphogenesis, showing their interaction is required for netrin responses.

Distinct developmental phenotypes result from mutation of Set8/KMT5A and histone H4 lysine 20 in Drosophila melanogaster

This study shows that Set8/KMT5A and H4K20me1 have distinct roles in Drosophila development, with non-catalytic functions of Set8 and H4K20me1 contributing to viability and phenotypic differences.

Semaphorin3F Drives Dendritic Spine Pruning through Rho-GTPase Signaling

This study identifies Sema3F's role in dendritic spine pruning through Rho-GTPase signaling pathways in cortical neurons.

Cdt1 variants reveal unanticipated aspects of interactions with Cyclin/CDK and MCM important for normal genome replication.

The paper investigates Cdt1 variants associated with Meier-Gorlin syndrome and a Drosophila allele to uncover their effects on MCM loading, Cyclin/CDK interactions, and genome replication.