Author

Ang Chen

Peking UniversityORCID 0000-0002-8975-5113Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Binrui Mo· 1 shared Jie ChengiD· 1 shared Tao Xu· 1 shared Wensheng WeiiD· 1 shared Xuran NiuiD· 1 shared Ying LiuiD· 1 shared Yingyan YuiD· 1 shared Yizhou LiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Binrui Mo

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1 paper

Recent·Most cited

Massively parallel interrogation of human functional variants modulating cancer immunosurveillance

Ying Liu, Yongshuo Liu, Xuran Niu, Ang Chen, Yizhou Li, Yingyan Yu, Binrui Mo, Zhiheng Liu, Tao Xu, Jie Cheng, Zeguang Wu, Wensheng Wei

The paper identifies functional mutations affecting PD-L1 and HLA-I expression using a large-scale CRISPR screen, revealing clinically relevant variants that influence immunotherapy response.

Signal Transduction and Targeted Therapy · Mar 18, 2025Peer-reviewedCancer Biology