Author

Binrui Mo

Peking University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Wensheng WeiiD· 2 shared Xuran NiuiD· 2 shared Ying LiuiD· 2 shared Yongshuo LiuiD· 2 shared Ang CheniD· 1 shared Jie ChengiD· 1 shared Tao Xu· 1 shared Wei Dong TangiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Wensheng WeiORCID

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2 papers

Recent·Most cited

Massively parallel interrogation of human functional variants modulating cancer immunosurveillance

Ying Liu, Yongshuo Liu, Xuran Niu, Ang Chen, Yizhou Li, Yingyan Yu, Binrui Mo, Zhiheng Liu, Tao Xu, Jie Cheng, Zeguang Wu, Wensheng Wei

The paper identifies functional mutations affecting PD-L1 and HLA-I expression using a large-scale CRISPR screen, revealing clinically relevant variants that influence immunotherapy response.

Signal Transduction and Targeted Therapy · Mar 18, 2025Peer-reviewedCancer Biology

Prime editor-based high-throughput screening reveals functional synonymous mutations in the human genome

Xuran Niu, Wei Dong Tang, Yongshuo Liu, Ying Liu, Binrui Mo, Ying Yu, Wensheng Wei

The paper uses Prime editor-based screening to identify functional synonymous mutations in the human genome, showing some affect cell fitness and biological processes.

bioRxiv · Jun 16, 2024 · PreprintGenetics