Author

Yongshuo Liu

Peking UniversityORCID 0000-0001-8190-0139Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Binrui Mo· 2 shared Wensheng WeiiD· 2 shared Xuran NiuiD· 2 shared Ying LiuiD· 2 shared Ang CheniD· 1 shared Jie ChengiD· 1 shared Tao Xu· 1 shared Wei Dong TangiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Binrui Mo

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2 papers

Recent·Most cited

Cancer BiologySignal Transduction and Targeted TherapyPeer-reviewedMar 18, 2025

Massively parallel interrogation of human functional variants modulating cancer immunosurveillance

Ying Liu, Yongshuo Liu, Xuran Niu…·Wensheng Wei

The paper identifies functional mutations affecting PD-L1 and HLA-I expression using a large-scale CRISPR screen, revealing clinically relevant variants that influence immunotherapy response.

8 citations

humanwhole-genome sequencing

𝕏 PostBluesky

GeneticsbioRxivPreprintJun 16, 2024

Prime editor-based high-throughput screening reveals functional synonymous mutations in the human genome

Xuran Niu, Wei Dong Tang, Yongshuo Liu…·Wensheng Wei

The paper uses Prime editor-based screening to identify functional synonymous mutations in the human genome, showing some affect cell fitness and biological processes.

3 citations

humanexperimental assay

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