Author

Neha Changela

Rutgers, The State University of New Jersey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 4 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 5 Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Janet Ko JangiD· 4 shared Kim S. McKimiD· 4 shared Jay N. JoshiiD· 2 shared Joanatta G. Shapiro· 2 shared Tyler Defosse· 2 shared Aashka Parikh· 1 shared Arunika DasiD· 1 shared Ayla Boyd· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersGenetics

Janet Ko JangORCID

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Author profile →

5 papers

Recent·Most cited

Distinct checkpoint and homolog biorientation pathways regulate meiosis I in Drosophila oocytes

Joanatta G. Shapiro, Neha Changela, Janet Ko Jang, Jay N. Joshi, Kim S. McKim

This study investigates SAC function and biorientation pathways in Drosophila meiosis I, finding SAC is not required for chromosome segregation but some SAC proteins are involved in biorientation.

PLoS Genetics · Jan 29, 2025Peer-reviewedGenetics

Meiosis-specific functions of kinetochore protein SPC105R required for chromosome segregation in Drosophila oocytes

Jay N. Joshi, Neha Changela, Lia Mahal, Janet Ko Jang, Tyler Defosse, Lin-Ing Wang, Arunika Das, Joanatta G. Shapiro, Kim S. McKim

This study identifies specific domains of SPC105R critical for meiosis I chromosome segregation in Drosophila oocytes by analyzing its functional regions and interactions.

Molecular Biology of the Cell · Jun 12, 2024Peer-reviewedGenetics

Tet-dependent 5-hydroxymethyl-Cytosine modification of mRNA regulates axon guidance genes in Drosophila

Badri Nath Singh, Hiep Tran, Joseph Kramer, Elmira Kirichenko, Neha Changela, Fei Wang, Yaping Feng, Dibyendu Kumar, Min Tu, Jie Lan, Martin Bizet, François Fuks, Ruth Steward

This study identifies Tet-dependent 5-hydroxymethylcytosine (5hmrC) modifications on mRNAs in Drosophila and shows their role in regulating axon guidance genes.

PLoS ONE · Feb 21, 2024Peer-reviewedGenomics

A Dynamic population of prophase CENP-C is required for meiotic chromosome segregation

Jessica E. Fellmeth, Janet Ko Jang, Manisha Persaud, Hannah Sturm, Neha Changela, Aashka Parikh, Kim S. McKim

This study shows that CENP-C must be expressed during meiotic prophase to ensure proper chromosome segregation, unlike CID which remains stable without prophase expression.

PLoS Genetics · Nov 29, 2023Peer-reviewedGenetics

Whole Transcriptome and Functional Analyses Identify Novel Genes Involved in Meiosis and Fertility in Drosophila melanogaster

Siqi Sun, Tyler Defosse, Ayla Boyd, Joel Sop, Faith Verderose, Diya Surray, Mark Aziz, Margaret Howland, Siwen Wu, Neha Changela, Janet Ko Jang, Karen Schindler, Jinchuan Xing, Kim S. McKim

The paper identifies 65 novel meiotic and fertility genes in Drosophila melanogaster through RNAi screening, showing their role in infertility and chromosomal nondisjunction.

bioRxiv · May 12, 2023 · PreprintGenetics