Author

Witold Rzyman

Gdańsk Medical UniversityORCID 0000-0002-9044-7791Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Anna BiernackaiD· 1 shared Anna LalikiD· 1 shared Artur PirógiD· 1 shared Babasaheb P. Sonwane· 1 shared Daria KostkaiD· 1 shared Ines PapakiD· 1 shared Jakub FaktoriD· 1 shared Khanh Ngoc DinhiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Anna BiernackaORCID

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2 papers

Recent·Most cited

Correction of the cytosine deamination artifacts in FFPE-based sequencing experiments

Wiktoria Płonka, Daria Kostka, Anna Lalik, Monika Kurpas, Khanh Ngoc Dinh, Magdalena Sitkiewicz, Marek Kimmel, Witold Rzyman, Roman Jaksik

This study evaluates methods to correct cytosine deamination artifacts in FFPE sequencing, finding enzymatic repair is most effective and FFPErase is the best computational method.

bioRxiv · Aug 19, 2026 · PreprintBioinformatics

Benchmarking five extracellular vesicle proteomics workflows, including low-input Exo-insert and Exo-SP3, for deep mass spectrometry profiling

Jakub Faktor, Artur Piróg, Anna Biernacka, Ines Papak, Swapnil Bhasvar, Babasaheb P. Sonwane, Tomasz Marjański, Witold Rzyman, Natalia-Marek Trzonkowska, Sachin Kote

The paper benchmarks five proteomics workflows for sEV analysis, showing Exo-insert and Exo-SP3 can identify ~1100 proteins from low-input samples, with performance varying by sEV source.

bioRxiv · May 28, 2026 · PreprintCancer Biology