Author

Zhangxin Chen

Peking UniversityORCID 0000-0002-9107-1925Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:diffusion model· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Chao ShiiD· 1 shared Hejian ZhangiD· 1 shared Hong Yi ChangiD· 1 shared Huanyu ChuiD· 1 shared Huifeng JiangiD· 1 shared Jian ChengiD· 1 shared Jie BaiiD· 1 shared Jing Li· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Chao ShiORCID

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1 paper

Recent·Most cited

Cytochrome P450 Enzyme Design by Constraining Catalytic Pocket in Diffusion model

Qian Wang, Xiaonan Liu, Hejian Zhang, Huanyu Chu, Chao Shi, Lei Justan Zhang, Pi Liu, Jing Li, Xiaoxi Zhu, Yuwan Liu, Zhangxin Chen, Rong Huang, Jie Bai, Hong Yi Chang, Tian Liu, , Huifeng Jiang

The paper designs artificial cytochrome P450 enzymes by applying a 'three-point fixation' model derived from structural and evolutionary analysis, resulting in enzymes with enhanced catalytic activity.

bioRxiv · Jan 8, 2024 · PreprintMolecular Biology