Author

Michael O’Reilly

Royal College of Surgeons in IrelandORCID 0000-0002-9108-9105Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

AE TayloriD· 1 shared Amarah V. AnthonyiD· 1 shared Ana Cristina VargasiD· 1 shared Andrea WagenfeldiD· 1 shared Antonio M. A. MirandaiD· 1 shared Christine Louise ChafferiD· 1 shared Eka MelsoniD· 1 shared Emir BozkurtiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

AE TaylorORCID

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2 papers

Recent·Most cited

Inhibition of the androgen-activating enzyme AKR1C3 selectively decreases systemic and intra-adipose 11-oxygenated androgens in women

Lina Schiffer, Amarah V. Anthony, Laura B. L. Wittemans, AE Taylor, Imken Oestlund, Antonio M. A. Miranda, Eka Melson, Tara McDonnell, Punith Kempegowda, Paul Smith, T. Justin Clark, Martin Wabitsch, Michael O’Reilly, Michaele Peters, Andrea Wagenfeld, , Wiebke Arlt

Inhibition of AKR1C3 reduces 11-oxygenated androgens but not classic androgens in women.

bioRxiv · Mar 30, 2026 · PreprintPhysiology

Androgen receptor interactions provide insight into steroid mediated metabolic shifts in endocrine resistant breast cancer.

Rachel Bleach, Emir Bozkurt, Jingqi Xin, Katherine M. Sheehan, Sally L. Shirran, Stephanie Agbana, Mihaela Ola, Leonie S. Young, Nicole S. Spoelstra, Jennifer K. Richer, Ana Cristina Vargas, Leonard D. Goldstein, Heloisa Helena Milioli, Christine Louise Chaffer, Michael O’Reilly, , Marie McIlroy

This study identifies cytoplasmic androgen receptor (AR) localization and novel AR protein interactions in AI-resistant breast cancer, linking them to metabolic shifts and poor prognosis.

npj Breast Cancer · Mar 17, 2026Peer-reviewedCancer Biology