Heloisa Helena Milioli

This study identifies cytoplasmic androgen receptor (AR) localization and novel AR protein interactions in AI-resistant breast cancer, linking them to metabolic shifts and poor prognosis.

This paper shows that NDRG1 suppresses pancreatic cancer metastasis by disrupting exosome-mediated communication between cancer cells and the tumor microenvironment.

This study identifies JNK pathway suppression as a driver of resistance to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer, with implications for patient stratification.

This study shows that Decitabine suppresses tumour growth in ER+ breast cancer by inducing DNA hypomethylation and altering 3D chromatin structure.

The paper uses multi-modal transcriptomic data to show basal breast cancer exhibits hybrid epithelial/mesenchymal states and higher phenotypic heterogeneity compared to luminal breast cancer.