Author

Charlotte C.G. Ho

Mayo Clinic in FloridaORCID 0000-0002-9135-1652Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Approach:benchmark study· 2 Assay:bulk RNA-seq· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Mariet AlleniD· 4 shared Nilüfer Ertekin‐TaneriD· 4 shared Zachary QuicksalliD· 4 shared Dennis W. DicksoniD· 3 shared Joseph S. ReddyiD· 3 shared Minerva M. CarrasquilloiD· 3 shared Stephanie R. Oatman· 3 shared Thuy NguyeniD· 3 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Mariet AllenORCID

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Author profile →

4 papers

Recent·Most cited

Large- Scale Deep Proteomic Analysis in Alzheimer's Disease Brain Regions Across Race and Ethnicity

Fatemeh Seifar, Edward J. Fox, Anantharaman Shantaraman, Yue Liu, Eric B. Dammer, Erica S. Modeste, Duc M. Duong, Luming Yin, Adam N. Trautwig, Qi Jin Guo, Kaiming Xu, Lingyan Ping, Joseph S. Reddy, Mariet Allen, Zachary Quicksall, , Nicholas T. Seyfried

The paper performs large-scale proteomic analysis of Alzheimer's disease brain regions across different racial and ethnic groups, identifying AD-related protein changes and APOE4 concordance with genotype.

Alzheimer s & Dementia · Nov 13, 2024Peer-reviewedNeuroscience

Bridging the Gap: Multi-Omics Profiling of Brain Tissue in Alzheimer's Disease and Older Controls in Multi-Ethnic Populations

Joseph S. Reddy, Laura M. Heath, Abby Vander Linden, Mariet Allen, Kátia de Paiva Lopes, Fatemeh Seifar, Erming Wang, Yiyi Ma, William L. Poehlman, Zachary Quicksall, Alexi M. Runnels, Yanling Wang, Duc M. Duong, Luming Yin, Kaiming Xu, , Nilüfer Ertekin‐Taner

This paper presents a multi-omics dataset from multi-ethnic Alzheimer's disease brain donors, including transcriptome, genome, and proteome data, to improve precision medicine for underrepresented populations.

Alzheimer s & Dementia · Aug 30, 2024Peer-reviewedNeuroscience

Single Nuclei Transcriptome Reveals Perturbed Brain Vascular Molecules in Alzheimer's Disease

Özkan İş, Xue Wang, Tulsi Patel, Zachary Quicksall, Michael G. Heckman, Launia J. White, Laura J. Lewis‐Tuffin, Kaancan Deniz, Frederick Q Tutor‐New, Troy Carnwath, Yuhao Min, Stephanie R. Oatman, Joseph S. Reddy, Minerva M. Carrasquillo, Thuy Nguyen, , Nilüfer Ertekin‐Taner

The paper uses single nucleus RNA sequencing to analyze brain vascular cells in Alzheimer's disease, identifying molecular changes and interactions between vascular and astrocytic cells at the blood-brain barrier.

bioRxiv · Dec 28, 2021 · PreprintNeuroscience

Transcriptional landscape of human microglia reveals robust gene expression signatures that implicates age, sex and APOE-related immunometabolic pathway perturbations

Tulsi Patel, Troy Carnwath, Xue Wang, Mariet Allen, Sarah Lincoln, Laura J. Lewis‐Tuffin, Zachary Quicksall, Shu Lin, Frederick Q Tutor‐New, Charlotte C.G. Ho, Yuhao Min, Kimberly G. Malphrus, Thuy Nguyen, Elizabeth Martin, César A. Garcia, , Nilüfer Ertekin‐Taner

The paper characterizes human microglia transcriptomes and identifies gene expression signatures linked to age, sex, and APOE-ε4, revealing immunometabolic pathway perturbations in neurodegeneration.

bioRxiv · May 13, 2021 · PreprintGenetics