Author

Mahmoud Moustafa

Suez Canal UniversityORCID 0000-0002-9146-0808Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Amir AbdollahiiD· 3 shared Juergen DebusiD· 3 shared Andrea MairaniiD· 2 shared Ivana ĐokićiD· 2 shared Mahdi AkbarpouriD· 2 shared Thomas TessonnieriD· 2 shared Alexander YounsiiD· 1 shared Andreas Unterberg· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCancer Biology

Amir AbdollahiORCID

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3 papers

Recent·Most cited

Cancer BiologyScience Translational MedicinePeer-reviewedMar 4, 2026

Personalized Medicine for Meningiomas: Drug Screening on Tumor Organoids Exposes Therapeutic Vulnerabilities to HDAC1/2i Panobinostat

Gerhard Jungwirth, Junguo Cao, Yimin Pan…·Christel C. Herold‐Mende

This study identifies panobinostat as an effective treatment for aggressive meningiomas through drug screening on tumor organoids and reveals a resistance mechanism involving the HDAC8-TGFβ-EMT axis.

6 citationstop 1%

humanbulk RNA-seq

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Cancer BiologyPhysics and Imaging in Radiation OncologyPeer-reviewedJul 1, 2025

Exploring High LET Oxygen-Ion FLASH Radiation for Targeting Pancreatic Cancer in Vitro and In Vivo

Celine Karle, Domenico Ivan Filosa, Mahdi Akbarpour…·Ivana Đokić

This study evaluates oxygen-ion FLASH radiation for in vitro and in vivo pancreatic cancer treatment, showing comparable tumor cell killing to standard dose rates.

2 citations

humanexperimental assay

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Cell BiologyMolecular Cancer TherapeuticsPeer-reviewedDec 31, 2024

Ultra-High Dose Rate Helium Ion Beams: Minimizing Brain Tissue Damage while Preserving Tumor Control

Ivana Đokić, Mahmoud Moustafa, Thomas Tessonnier…·Amir Abdollahi

This study compares ultra-high-dose rate helium ion radiotherapy (FLASH) with standard dose rate (SDR) in mice, showing FLASH reduces brain injury and neuroinflammation while maintaining tumor control.

13 citations

mouseexperimental assay

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