Author

Jiankun Zhang

Peking UniversityORCID 0000-0002-9147-2569Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:DNA methylation· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Assay:CUT&Tag· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Xiaoliang Sunney XieiD· 3 shared Fanchong JianiD· 2 shared Honggui WuiD· 2 shared Jun ReniD· 2 shared Runsheng He· 2 shared Shuang LiuiD· 2 shared Wenyang Dong· 2 shared Yuxuan PangiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersGenomics

Xiaoliang Sunney XieORCID

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3 papers

Recent·Most cited

Extruding transcription elongation loops observed in high-resolution single-cell 3D genomes

Honggui Wu, Jiankun Zhang, Longzhi Tan, Xiaoliang Sunney Xie

The paper uses single-cell 3D genome mapping to show cohesin-mediated loop extrusion forms transcription elongation loops that enhance transcriptional burst frequency.

Nature Genetics · Jul 1, 2025Peer-reviewedGenomics

Mapping eukaryotic chromatin accessibility and histone modifications with DNA deaminase

Wenyang Dong, Jiankun Zhang, Leyi Dai, Jinxin Phaedo Chen, Honggui Wu, Runsheng He, Yuxuan Pang, Zhi Wang, Fanchong Jian, Jun Ren, Yijun Liu, Yu Tian, Shuang Liu, Xuechen Zhao, Xiaoliang Sunney Xie

The paper introduces two new methods, ChrODIE and ANDIE, for mapping chromatin accessibility and histone modifications without enzymatic cleavage, enabling multi-omics integration.

bioRxiv · Dec 24, 2024 · PreprintGenomics

Human transcription factor combinations mapped by footprinting with deaminase

Runsheng He, Wenyang Dong, Zhi Wang, Chen Xie, Long Gao, Wenping Ma, Ke Shen, Dubai Li, Yuxuan Pang, Fanchong Jian, Jiankun Zhang, Yuan Yuan, Xinyao Wang, Zhen Zhang, Yinghui Zheng, , Xiaoliang Sunney Xie

The paper introduces a method to map transcription factor binding sites genome-wide with single-base resolution and applies it to study cell-type-specific TF cooperativity in human tissues.

Proceedings of the National Academy of Sciences · Dec 17, 2024Peer-reviewedGenomics