Nathan J. Hillson

Binary vector origin predictably determines Agrobacterium-mediated transformation outcome across eukaryotic kingdoms

This study shows that binary vector origin of replication family, not copy number, determines Agrobacterium-mediated transformation outcomes across plants and fungi.

Bioinformatic prediction and high throughput in vivo screening to identify cis-regulatory elements for the development of algal synthetic promoters

The paper identifies cis-regulatory elements in algae to create synthetic promoters, validated through in vivo testing and high-throughput screening.

Scalable and Automated CRISPR-Based Strain Engineering Using Droplet Microfluidics

The paper describes a microfluidic system for high-throughput CRISPR-based gene editing and screening, demonstrating its ability to perform parallel genetic modifications in E. coli.

Multiomics data collection, visualization, and utilization for guiding metabolic engineering

The paper presents tools for storing, visualizing, and leveraging multiomics data to predict outcomes of bioengineering efforts.