Molecular BiologybioRxivPreprint
Damaging the conical morphology of HIV-1 capsid by targeting the FG-binding pocket and disfavoring pentameric subunits needed for core closure
William M. McFadden, Karen A. Kirby, Zachary C. Lorson…·Stefan G. Sarafianos
This study investigates how ZW-1261, an FGBP-targeting inhibitor, disrupts HIV-1 capsid morphology by affecting pentameric subunits and core closure.
DOI 10.64898/2026.03.19.712970