Robert A. Dick

This study shows that retroviral CA subdomains encode immature assembly properties independently, without requiring strict co-pairing or co-evolution between subdomains.

This study uses cryo-electron tomography to analyze the structural organization of Nipah virus proteins in virus-like particles, revealing novel interactions and structural features.

This paper reports cryo-EM structures of HIV-1 RT during PPT strand displacement, revealing the mechanism and key residues involved in the process.

This study investigates how ZW-1261, an FGBP-targeting inhibitor, disrupts HIV-1 capsid morphology by affecting pentameric subunits and core closure.

This study investigates how Lenacapavir disrupts HIV-1 assembly and maturation, revealing a 'premature' lattice formation that prevents infectious virus production.

This paper investigates how HIV capsid core translocates through the Nuclear Pore Complex by analyzing FG repeat interactions and identifies an affinity gradient that facilitates unidirectional translocation.

This study identifies SP2 as a trigger for HIV-1 MA lattice maturation, showing it binds MA to induce structural changes and enhance viral infectivity.

This paper identifies an unconventional stabilization mechanism in HTLV-1 immature Gag lattice using cryo-ET and mutagenesis, showing CA-NTD as the primary stabilizing component.

The paper evaluates the performance of new cryo-EM hardware for cryo-ET and subtomogram averaging using EIAV virus-like particles, showing comparable resolution and improved reconstructions with advanced processing methods.

The paper investigates the role of IP6 in RSV capsid assembly, showing it promotes hexamer formation and is critical for infectivity.