Author

Marion H. C. Wijering

University Medical Center GroningenORCID 0000-0002-9283-3952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Anneke MiedemaiD· 2 shared Bart J. L. EggeniD· 2 shared Emma GerritsiD· 2 shared Evelyn M. Wesseling· 2 shared Michel Meijer· 2 shared Susanne M. KooistraiD· 2 shared Anna T. E. Pijnacker· 1 shared Astrid M. AlsemaiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersNeuroscience

Anneke MiedemaORCID

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2 papers

Recent·Most cited

Identification of regional astrocyte heterogeneity associated with cuprizone-induced de- and remyelination using spatial transcriptomics

Anneke Miedema, Marion H. C. Wijering, Astrid M. Alsema, Emma Gerrits, Michel Meijer, Mirjam Koster, Evelyn M. Wesseling, Wia Baron, Bart J. L. Eggen, Susanne M. Kooistra

This paper uses spatial transcriptomics to identify regional astrocyte heterogeneity in cuprizone-induced demyelination and remyelination, revealing differential gene expression patterns across brain regions.

bioRxiv · Mar 4, 2024 · PreprintNeuroscience

Brain macrophages acquire distinct transcriptomes prior to demyelination in multiple sclerosis

Anneke Miedema, Emma Gerrits, Nieske Brouwer, Qiong Jiang, Laura Kracht, Michel Meijer, Erik Nutma, Regina M. B. Peferoen-Baert, Anna T. E. Pijnacker, Evelyn M. Wesseling, Marion H. C. Wijering, Hans‐Joachim Gabius, Sandra Amor, Bart J. L. Eggen, Susanne M. Kooistra

The paper identifies early transcriptomic changes in brain macrophages in MS tissue, linking them to lesion development and suggesting potential therapeutic targets.

bioRxiv · Oct 27, 2021 · PreprintNeuroscience