Élodie Monsellier

The paper reports a large-scale quantitative interactome of human PDZ domains and bacterial PDZ-binding motifs, showing bacteria tailor effector sequences to bind with similar or higher affinity than human PBMs to hijack host functions.

This study shows that glucocorticoid receptor (GR) interacts with androgen receptor (AR) to regulate prostate epithelial homeostasis through shared cis-regulatory elements.

This study identifies MOSPD2-STARD3 as a functional unit regulating late endosome/lysosome dynamics and cholesterol homeostasis through selective interaction at ER contact sites.

The paper introduces a high-throughput mass-spectrometry-based assay to measure protein-ligand affinity constants, demonstrating its application to 14-3-3 isoforms and phosphopeptides.

The paper measures affinities of 65,000 PDZ domain interactions using quantitative fragmentomics, revealing viral interference hotspots and system-wide impacts of interactome hijacking.

ProFeatMap provides a customizable 2D visualization tool for protein features, enabling users to explore domain and modification information from a list of proteins.