Fahong Yu

Vps35 p.D620N causes Lrrk2 kinase hyperactivity, chronic microglial activation and inflammation

This study investigates the effects of Vps35 p.D620N mutation on microglial function, showing increased LRRK2 kinase activity, chronic inflammation, and altered immune responses in mice.

Fibro-Adipogenic Progenitors require autocrine IGF-I in homeostatic and regenerating skeletal muscle

This study shows that autocrine IGF-I is essential for FAP function in muscle homeostasis and regeneration, with loss of IGF-I leading to impaired regeneration and altered FAP properties.

Extracellular salicylic acid activates immune signaling through cell-surface receptors

This study shows extracellular salicylic acid activates immune signaling via cell-surface receptors LecRK-I.8 and LecRK-VI.2 in Arabidopsis.