Eppu Manninen

Separable multidimensional MRI signatures of cellular and structural pathology in Alzheimer's disease

This study links multidimensional MRI signatures to histological pathology in Alzheimer's disease, showing distinct diffusion-relaxation patterns associated with specific cellular and structural changes.

Multidimensional MRI reveals cellular-scale microstructural phenotypes in human brain aging

This study uses multidimensional MRI to analyze cellular-scale microstructural changes in the human brain across aging, revealing increased heterogeneity and loss of microscopic restriction.

Ex vivo massively multidimensional diffusion-relaxation correlation MRI: scan-rescan reproducibility and caveats

This study evaluates the reproducibility of MMD-MRI metrics in ex vivo mouse brains and identifies fixation time effects.

In vivo disentanglement of diffusion frequency-dependence, tensor shape, and relaxation using multidimensional MRI

This paper introduces an efficient in vivo MD-MRI protocol for whole-brain imaging and demonstrates its feasibility and robustness using phantoms and human scans.

The variability of multidimensional diffusion-relaxation MRI estimates in the human brain

This paper evaluates the reliability and reproducibility of multidimensional diffusion-relaxation MRI (MD-MRI) in the human brain, showing it can reliably capture structural and chemical diversity within voxels.

Automatic segmentation of the rat brain hippocampus in MRI after traumatic brain injury

The paper develops a CNN-based method for automated hippocampus segmentation in rat MRI images post-TBI, showing superior performance compared to registration-based methods.