Dan Benjamini

Multidimensional T1-T2 Relaxation Imaging In Vivo on a Portable 0.064~T MRI Scanner

This paper demonstrates whole-brain multidimensional T1-T2 relaxation imaging on a portable 0.064 T MRI scanner, showing that joint distributions provide additional information beyond single-value relaxation maps.

Multidimensional diffusion MRI reveals heterogeneous microstructural remodeling associated with amyloid pathology

This study uses multidimensional diffusion MRI to show increased microstructural heterogeneity in 5xFAD mouse brains compared to wild-type, associated with amyloid pathology but not widespread degeneration.

Separable multidimensional MRI signatures of cellular and structural pathology in Alzheimer's disease

This study links multidimensional MRI signatures to histological pathology in Alzheimer's disease, showing distinct diffusion-relaxation patterns associated with specific cellular and structural changes.

Multidimensional MRI reveals cellular-scale microstructural phenotypes in human brain aging

This study uses multidimensional MRI to analyze cellular-scale microstructural changes in the human brain across aging, revealing increased heterogeneity and loss of microscopic restriction.

Widespread gray and white matter microstructural alterations in dual cognitive-motor impairment

This study identifies widespread microstructural changes in gray and white matter in individuals with dual cognitive-motor impairment compared to isolated impairments and controls.

Data Processing in Multidimensional MRI For BiomarkerIdentification: Is It Necessary?

This study compares the effectiveness of using raw MD-MRI signals versus reconstructed spectra for statistical regression in biomarker identification, concluding that signals are more effective without prior information.

Ex vivo massively multidimensional diffusion-relaxation correlation MRI: scan-rescan reproducibility and caveats

This study evaluates the reproducibility of MMD-MRI metrics in ex vivo mouse brains and identifies fixation time effects.

Resiliency to Alzheimer's disease neuropathology can be distinguished from dementia using cortical astrogliosis imaging

This study uses MD-MRI to map cortical astrogliosis and distinguishes cognitive resilience from dementia in Alzheimer's disease despite significant neuropathology.

In vivo disentanglement of diffusion frequency-dependence, tensor shape, and relaxation using multidimensional MRI

This paper introduces an efficient in vivo MD-MRI protocol for whole-brain imaging and demonstrates its feasibility and robustness using phantoms and human scans.

Neuronal microstructural changes in the human brain are associated with neurocognitive aging

This study uses diffusion MRI to identify microstructural changes in the human brain associated with neurocognitive aging, finding that microstructural markers are more strongly linked to cognitive performance than macrostructural changes.

The variability of multidimensional diffusion-relaxation MRI estimates in the human brain

This paper evaluates the reliability and reproducibility of multidimensional diffusion-relaxation MRI (MD-MRI) in the human brain, showing it can reliably capture structural and chemical diversity within voxels.

Astrogliosis mapping in individual brains using multidimensional MRI

This paper develops a machine learning framework to map astrogliosis in individual brains using multidimensional MRI, showing strong correlation with histological findings.

Multidimensional MRI for characterization of subtle axonal injury accelerated using an adaptive nonlocal multispectral filter

This paper evaluates a filter to reduce scan time in multidimensional MRI by improving noise reduction and accuracy of injury biomarker maps.

Direct and specific assessment of axonal injury and spinal cord microenvironments using diffusion correlation imaging

This paper introduces a 2D diffusion MRI framework to specifically assess axonal injury and spinal cord microenvironments, showing strong correlation with histological findings.