Author

Pooja Manjunath

University of HelsinkiORCID 0000-0002-9449-6443Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Henna TyynismaaiD· 2 shared Eija PirineniD· 1 shared Gorazd StojkovičiD· 1 shared Jayasimman RajendraniD· 1 shared Jonna Saarimäki‐VireiD· 1 shared Jouni KvistiD· 1 shared Kalle Luopajärvi· 1 shared Liliya EuroiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPhysiology

Henna TyynismaaORCID

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2 papers

Recent·Most cited

Loss of mitochondrial co-chaperone GRPEL2 protects mice from age- and diet-induced obesity

Yang Yang, Nirajan Neupane, Jouni Kvist, Jonna Saarimäki‐Vire, Matthias Schewe, Kalle Luopajärvi, Pooja Manjunath, Svetlana Konovalova, Rubén Torregrosa‐Muñumer, Veijo Kinnunen, Pekka Katajisto, Timo Otonkoski, Eija Pirinen, Jayasimman Rajendran, Henna Tyynismaa

This study shows that loss of GRPEL2 in mice protects against age- and diet-induced obesity and improves metabolic health without affecting mitochondrial protein import.

Mitochondrion · Aug 22, 2026Peer-reviewedPhysiology

Preferential binding of ADP-bound mitochondrial HSP70 to the nucleotide exchange factor GRPEL1 over GRPEL2

Pooja Manjunath, Gorazd Stojkovič, Liliya Euro, Svetlana A. Konovalova, Sjoerd Wanrooij, M. Kristian Koski, Henna Tyynismaa

This study shows ADP-bound mtHSP70 binds preferentially to GRPEL1 over GRPEL2, with structural insights into their functional differences.

Protein Science · Oct 24, 2024Peer-reviewedBiochemistry