Predicting mechanism of action of cellular perturbations with pathway activity signatures
Yan Ren, Siva Sivaganesan, Nicholas A. Clark, Lixia Zhang, Jacek Biesiada, Wen Niu, David R. Plas, Mario Medvedovic
The paper develops a method to predict the mechanism of action of cellular perturbations by analyzing pathway network topology and transcriptional signatures.
Bioinformatics · Jul 3, 2020Peer-reviewedSystems Biology