Author

Chao-Tsung Yang

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:zebrafish· 3 Assay:imaging· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Misha B. AhrensiD· 3 shared Amy E. KeatingiD· 1 shared Andreas Savas ToliasiD· 1 shared Armin BahliD· 1 shared Burcu Guner‐Ataman· 1 shared Caroline Lei WeeiD· 1 shared Changyang LinghuiD· 1 shared Chi-Ling Teng· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersNeuroscience

Misha B. AhrensORCID

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Author profile →

4 papers

Recent·Most cited

A Suite of Biochemical and Cell-Based Assays for the Characterization of KRAS Inhibitors and Degraders

Medhanie Kidane, Rene M. Hoffman, Jennifer K. Wolfe-Demarco, Ting-Yu Huang, Chi-Ling Teng, Saheli Samanta, Luis M. Gonzalez Lira, Jennifer Lin‐Jones, Gabriel Pallares, Jane E. Lamerdin, Nicole B. Servant, Chun-Yao Lee, Chao-Tsung Yang, Jean A. Bernatchez

The paper develops biochemical and cell-based assays to evaluate KRAS inhibitors and degraders, generating selectivity profiles and dissociation constants for various KRAS mutants.

ACS Pharmacology & Translational Science · Dec 2, 2024Peer-reviewedPharmacology & Toxicology

Precision calcium imaging of dense neural populations via a cell body-targeted calcium indicator

Or A. Shemesh, Changyang Linghu, Kiryl D. Piatkevich, Daniel Goodwin, Orhan T. Celiker, Howard J. Gritton, Michael F. Romano, Ruixuan Gao, Chih-Chieh Yu, Hua-an Tseng, Seth Bensussen, Sujatha Narayan, Chao-Tsung Yang, Limor Freifeld, Cody A. Siciliano, , Edward S. Boyden

The paper develops cell body-targeted calcium indicators to improve signal fidelity in one-photon imaging of neural activity in live mice and zebrafish.

Neuron · Jun 26, 2020Peer-reviewedNeuroscience

High-throughput cellular-resolution synaptic connectivity mapping in vivo with concurrent two-photon optogenetics and volumetric Ca2+ imaging

Christopher McRaven, Dimitrii Tanese, Lixia Zhang, Chao-Tsung Yang, Misha B. Ahrens, Valentina Emiliani, Minoru Koyama

The paper develops a high-throughput method to map synaptic connectivity in zebrafish using two-photon optogenetics and volumetric Ca2+ imaging.

bioRxiv · Feb 21, 2020 · PreprintNeuroscience

A bidirectional network for appetite control in larval zebrafish

Caroline Lei Wee, Erin Yue Song, Robert Evan Johnson, Deepak Ailani, Owen Randlett, Ji-Yoon Kim, Maxim Nikitchenko, Armin Bahl, Chao-Tsung Yang, Misha B. Ahrens, Koichi Kawakami, Florian Engert, Sam Martin Kunes

This study identifies a bidirectional interaction between hypothalamic nuclei in larval zebrafish that regulates hunger and satiety through opposing activity patterns.

eLife · Oct 17, 2019Peer-reviewedNeuroscience