Author

Dongyu Wu

Duke UniversityORCID 0000-0002-9463-7103Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Alan J. TackettiD· 1 shared Benjamin Aaron GarciaiD· 1 shared Bo PaniD· 1 shared Chenxi XuiD· 1 shared Gang Greg WangiD· 1 shared Jian Jun JiniD· 1 shared Kanishk JainiD· 1 shared Ling Cai· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alan J. TackettORCID

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1 paper

Recent·Most cited

YY1 relieves p300 autoinhibition to promote histone acetylation in advanced prostate cancer, enhancing the oncogenic signaling of Androgen Receptor Splice Variant 7

Chenxi Xu, Dongyu Wu, Bo Pan, Xiaoxiao Ren, Samuel G. Mackintosh, Kanishk Jain, Natarajan V. Bhanu, Ricky D. Edmondson, Xin Liu, Benjamin Aaron Garcia, Alan J. Tackett, Jian Jun Jin, Gang Greg Wang, Ling Cai

This study shows YY1 enhances p300 acetyltransferase activity in CRPC, promoting histone acetylation and oncogenic gene expression, and identifies a potential therapeutic target for overcoming drug resistance.

bioRxiv · Aug 4, 2025 · PreprintCancer Biology