Author

Lennart Brewitz

University of OxfordORCID 0000-0002-9465-777XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

Christopher John SchofieldiD· 2 shared A.P. TurnbulliD· 1 shared Adán Pinto-FernándeziD· 1 shared Alice Beard· 1 shared Andrea PierangeliniiD· 1 shared Anthony TumberiD· 1 shared Benedikt Mathias KessleriD· 1 shared Chuong NguyeniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Christopher John SchofieldORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 27, 2025

obABPP-HT*: A Precision-Engineered Activity Proteomics Pipeline for the Streamlined Discovery of Deubiquitinase Inhibitors

Hannah B. L. Jones, Simeon D. Draganov, Sofia Schönbauer Huamán…·Adán Pinto-Fernández

This paper introduces a high-throughput activity proteomics pipeline for discovering deubiquitinase inhibitors, identifying potent and selective inhibitors with minimal optimization.

2 citations

humanproteomics

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BioinformaticsRSC Chemical BiologyPeer-reviewedOct 24, 2023

Studies on the selectivity of the SARS-CoV-2 papain-like protease reveal the importance of the P2' proline of the viral polyprotein

H. T. Henry Chan, Lennart Brewitz, Petra Lukacik…·Fernanda Duarte

This study investigates how the P2' proline residue affects SARS-CoV-2 PLpro catalytic efficiency using molecular dynamics and substrate analysis.

10 citations

virusstatistical model

𝕏 PostBluesky