Author

Alexander M. Leipold

University of WürzburgORCID 0000-0002-9471-3276Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Assay:scRNA-seq· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Antoine‐Emmanuel SalibaiD· 3 shared Clément CochainiD· 2 shared Giuseppe RizzoiD· 2 shared Tobias KrammeriD· 2 shared Alexandra CirnuiD· 1 shared Alma ZerneckeiD· 1 shared Amruta Joshi· 1 shared Anna Rizakou· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

Antoine‐Emmanuel SalibaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Murine CMV Infection Unmasks Macrophage-Driven Inflammatory Cardiomyopathy in Pkp2, but not in Ttn Mutant Mice

Alexandra Cirnu, Tatjana Williams, Mike Noerpel, Julian Kammerer, Svenja Kannt, Mairin Heil, Laura Kimmel, Paula-Anahi Arias-Loza, Manivel Lhoda, Thomas Hennig, DiyaaElDin Ashour, Sarah‐Lena Puhl, Giuseppe Rizzo, Clément Cochain, Tobias Krammer, , Brenda Gerull

This study shows that murine cytomegalovirus infection exacerbates inflammation in Pkp2 mutant mice but not in Ttn mutant mice, highlighting the interaction between genetic predisposition and environmental factors in cardiomyopathy.

bioRxiv · Jan 28, 2026 · PreprintImmunology

Neutrophil terminal programming in the ischemic heart drives fibrosis after myocardial infarction

Marie Piollet, Giuseppe Rizzo, Ecem T. Sakalli, Jasmin El-Khabbaz, Mathis Gautier, Manuel Gendre, Ludovica Timperi, Anna Rizakou, Sourish Reddy Bandi, Tobias Krammer, Alexander M. Leipold, Jean‐Sébastien Silvestre, Antoine‐Emmanuel Saliba, Alma Zernecke, Clément Cochain

This study shows that neutrophils in the ischemic heart undergo terminal programming to drive fibrosis after myocardial infarction.

bioRxiv · Jan 15, 2026 · PreprintPhysiology

Prostate-specific membrane receptor PPAP facilitates E. coli invasion of luminal prostate cells via FimH binding

Maria Guedes, Amruta Joshi, Sina Dorn, Simon Peters, Tristan Beste, Alexander M. Leipold, Mathias Tillmann Rosenfeldt, Antoine‐Emmanuel Saliba, Ulrich Dobrindt, Charis Kalogirou, Carmen Aguilar

This study identifies PAPP as a receptor for UPEC FimH binding, enabling bacterial invasion of luminal prostate cells in a murine organoid model.

bioRxiv · Oct 28, 2024 · PreprintMolecular Biology