Ulrich Dobrindt

This study identifies renal mononuclear phagocytes as an intracellular reservoir for UPEC in pyelonephritis, showing that complement receptor-mediated entry promotes bacterial persistence and limits β-lactam efficacy.

The paper integrates kidney and urine proteomics with peptidomics and machine learning to identify encrypted antimicrobial peptides as functional effectors in human pyelonephritis.

This study shows colibactin-producing E. coli promote GEAC carcinogenesis by increasing proliferation, DNA damage, and cancer pathways, while also inducing autophagy and differentiation.

This study identifies PAPP as a receptor for UPEC FimH binding, enabling bacterial invasion of luminal prostate cells in a murine organoid model.

The paper compares brain lymphatic endothelial cells (BLECs) to scavenging endothelial cells (SECs) in the zebrafish and identifies Mrc1a as a key receptor for cargo uptake in BLECs.

The paper investigates the MPEC pathotype hypothesis by comparing genomes of bovine mastitis-associated E. coli and commensal isolates, finding no specific pathogenic traits unique to MAEC.