A generalizable normalization framework to decouple protocol and instrument effects: Application to high-sensitivity proteomics multicentric study (PME13)
Gianluca Arauz‐Garofalo, Sergio Ciordia, Anne Gonzalez de Peredo, Karima Chaoui, Jeewan Babu Rijal, Valeriane Gaxotte, Ignasi Folch-I-Casanovas, Mikel Azkargorta, Ruben Almey, Kerman Aloria, Busra Aytul Kirim, Rodrigo Barderas, Sophie Braga-Lagache, Enrique Calvo, Eduardo Chicano‐Gálvez, , Fernando José Corrales
This paper introduces a normalization framework to decouple protocol and instrument effects in multicenter proteomics studies, demonstrating its application to the PME13 dataset.
bioRxiv · Aug 20, 2026 · PreprintBioinformatics