Rodrigo Barderas

This paper introduces a normalization framework to decouple protocol and instrument effects in multicenter proteomics studies, demonstrating its application to the PME13 dataset.

The paper develops a workflow to detect and classify alternative microproteins in colorectal cancer cells, identifying biases in extraction methods and validating a subset experimentally.

This paper provides a step-by-step protocol for synthesizing and characterizing PAAm hydrogels of varying stiffness for cell culture and mechanobiology studies.

This study shows that matrix stiffness in colorectal cancer alters secreted protein expression, enhancing migration, angiogenesis, and matrix remodeling, contributing to a more aggressive cancer phenotype.

This study shows that nanoparticles behave differently in various tumor models, emphasizing the need to tailor their design based on tumor biology.

This study uses CRISPR to eliminate the FOXL2 c.402C>G mutation in granulosa tumor cells, reducing malignancy and identifying anti-tumoral compounds.