Chang‐Guo Zhan

Identification of scavenger receptor BI as a scavenger of free heme that is essential for protection against hemolysis

This study identifies scavenger receptor BI as a critical heme scavenger that protects against hemolysis, showing its therapeutic potential in hemolytic disorders.

Dimethylindanoylindole isomers revealed different pharmacological profiles at CB1 and CB2 cannabinoid receptors

The paper compares pharmacological profiles of dimethylindanoylindole isomers at CB1 and CB2 receptors using BRET assays and site-directed mutagenesis.

Tunable nucleofugality in carbamoyl-bearing covalent cholinesterase inhibitors

This study explores carbamoyl warhead reactivity in covalent cholinesterase inhibitors, identifying structure-reactivity relationships and demonstrating a highly selective, irreversible inhibitor.