Author

Alexander H. Williams

University of KentuckyORCID 0000-0002-0695-9947Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Chang‐Guo ZhaniD· 2 shared Ailing JiiD· 1 shared Bin HuangiD· 1 shared Chieko MineoiD· 1 shared Christopher LucajiD· 1 shared Dan Hao· 1 shared Gregory B. DudleyiD· 1 shared Hideaki YanoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPhysiology

Chang‐Guo ZhanORCID

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2 papers

Recent·Most cited

Identification of scavenger receptor BI as a scavenger of free heme that is essential for protection against hemolysis

Misa Ito, Jianyao Xue, Ling Guo, Dan Hao, Qian Wang, Alexander H. Williams, Chang‐Guo Zhan, Ailing Ji, Preetha Shridas, Wen Su, Shu Liu, Zhenheng Guo, M GONG, Scott M. Gordon, Bin Huang, , Xiang‐An Li

This study identifies scavenger receptor BI as a critical heme scavenger that protects against hemolysis, showing its therapeutic potential in hemolytic disorders.

Nature Communications · Jul 27, 2026Peer-reviewedPhysiology

Dimethylindanoylindole isomers revealed different pharmacological profiles at CB1 and CB2 cannabinoid receptors

Soo Jung Oh, Ruiru Guo, Christopher Lucaj, Neshira Gutierrez, Kh Tanvir Ahmed, Alexander H. Williams, Chang‐Guo Zhan, Gregory B. Dudley, Hideaki Yano

The paper compares pharmacological profiles of dimethylindanoylindole isomers at CB1 and CB2 receptors using BRET assays and site-directed mutagenesis.

ACS Bio & Med Chem Au · Jul 1, 2026Peer-reviewedPharmacology & Toxicology