Author

Henk L. M. Granzier

University of ArizonaORCID 0000-0002-9516-407XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Coen A. C. OttenheijmiD· 2 shared Jochen GohlkeiD· 2 shared Zaynab Hourani· 2 shared Esmat Karimi· 1 shared Eva L. PetersiD· 1 shared Johan LindqvistiD· 1 shared Joshua G. StromiD· 1 shared Ju CheniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

Coen A. C. OttenheijmORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The titin N2A-MARP signalosome constrains muscle longitudinal hypertrophy in response to stretch

Robbert J. van der Pijl, Jochen Gohlke, Joshua G. Strom, Eva L. Peters, Shengyi Shen, Stefan Conijn, Zaynab Hourani, Stephan Lange, Ju Chen, Paul R. Langlais, Siegfried Labeit, Henk L. M. Granzier, Coen A. C. Ottenheijm

The paper identifies MARPs as key modulators of titin-based mechanotransduction and shows mTORC1 regulates longitudinal muscle hypertrophy in response to stretch.

eLife · Jul 30, 2026Peer-reviewedPhysiology

Characterization of NEB mutations in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects

Esmat Karimi, Mila van der Borgh, Johan Lindqvist, Jochen Gohlke, Zaynab Hourani, Justin S. Kolb, Stacy A. Cossette, Michael William Lawlor, Coen A. C. Ottenheijm, Henk L. M. Granzier

This study characterizes NEB mutations in NEM2 patients, revealing mechanisms of nebulin dysfunction and the potential therapeutic benefit of Omecamtiv mecarbil.

bioRxiv · Dec 20, 2023 · PreprintGenetics