Anja Konietzny

Myosin VI controls localization of Golgi satellites at active presynaptic boutons

The paper investigates the presence and dynamic behavior of Golgi satellites in axons, showing they are transported bidirectionally and pause at presynaptic sites regulated by neuronal activity and myosin VI.

Efficient axonal trafficking of endolysosomes depends on the balanced ratio of microtubule tyrosination and detyrosination

The paper shows that disrupting the balance of microtubule tyrosination and detyrosination in neurons leads to defects in axonal transport and AIS length.

Synaptic anchoring of the endoplasmic reticulum depends on myosin V and caldendrin activity

The paper shows that synaptic ER stabilization depends on calmodulin and caldendrin regulating myosin V activity to control spine apparatus formation in active dendritic spines.

CAP2 is a novel regulator of Cofilin in synaptic plasticity and Alzheimer’s disease

This study identifies CAP2 as a regulator of Cofilin in synaptic plasticity, showing its role in LTP and its disruption in Alzheimer’s disease.

F-actin patches associated with glutamatergic synapses control positioning of dendritic lysosomes

The paper shows that actin patches at glutamatergic synapses create physical barriers that stall lysosome transport in dendrites.

Characterization of neuronal synaptopodin reveals a myosin V-dependent mechanism of synaptopodin clustering at the post-synaptic sites

This study identifies myosin V as essential for synaptopodin clustering at post-synaptic sites, showing that the spine apparatus is assembled locally rather than transported.