Efficient axonal trafficking of endolysosomes depends on the balanced ratio of microtubule tyrosination and detyrosination
Anja Konietzny, Leticia Peris, Yuhao Han, Yannes Popp, Bas van Bommel, Aditi Sharma, Philippe Delagrange, Nicolas Arbez, Marie‐Jo Moutin, Marina Mikhaylova
The paper shows that disrupting the balance of microtubule tyrosination and detyrosination in neurons leads to defects in axonal transport and AIS length.
bioRxiv · Oct 18, 2023 · PreprintNeuroscience