Author

Dmitry Torchinsky

Tel Aviv UniversityORCID 0000-0002-9568-6580Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:variant calling· 3 Organism:Arabidopsis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Elmar G. WeinholdiD· 4 shared Yael Michaeli· 4 shared Yuval EbensteiniD· 4 shared Matyas Juhasz· 3 shared Tslil GabrieliiD· 3 shared Alex R. HastieiD· 2 shared Assaf Grunwald· 2 shared Han CaoiD· 2 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenetics

Elmar G. WeinholdORCID

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4 papers

Recent·Most cited

Simultaneous global labeling (SiGL) of 5-methylcytosine and 5-hydroxymethylcytosine by DNA alkylation with a synthetic cofactor and engineered methyltransferase

Sigal Avraham, Leonie Schütz, Larissa Käver, Andreas Dankers, Sapir Margalit, Yael Michaeli, Shahar Zirkin, Dmitry Torchinsky, Noa Gilat, Omer Bahr, Gil Nifker, Maya Koren‐Michowitz, Elmar G. Weinhold, Yuval Ebenstein

The paper introduces a method to simultaneously analyze 5-methylcytosine and 5-hydroxymethylcytosine in clinical samples, showing reduced 5-hydroxymethylcytosine in colorectal cancer and chronic lymphocytic leukaemia.

bioRxiv · Oct 31, 2022 · PreprintGenetics

Chemoenzymatic labeling of DNA methylation patterns for single-molecule epigenetic mapping

Tslil Gabrieli, Yael Michaeli, Sigal Avraham, Dmitry Torchinsky, Sapir Margalit, Leonie Schütz, Matyas Juhasz, Ceyda Çoruh, Nissim Arbib, Zhaohui Sunny Zhou, Julie A. Law, Elmar G. Weinhold, Yuval Ebenstein

This paper develops a chemoenzymatic method to label non-methylated CpGs in DNA, enabling single-molecule epigenetic profiling in human and plant genomes.

Nucleic Acids Research · Jun 3, 2022Peer-reviewedGenomics

Reduced representation optical methylation mapping (R2OM2).

Assaf Grunwald, Hila Sharim, Tslil Gabrieli, Yael Michaeli, Dmitry Torchinsky, Rani Arieli, Matyas Juhasz, Kathryn R. Wagner, Jonathan Pevsner, Jeffrey G. Reifenberger, Alex R. Hastie, Han Cao, Elmar G. Weinhold, Yuval Ebenstein

R2OM2 creates fluorescent optical methylation profiles along chromosomal DNA for epigenetic profiling, comparable to WGBS with single-molecule resolution.

bioRxiv · Nov 16, 2017 · PreprintGenetics

Reduced representation optical methylation mapping (R2OM2).

Assaf Grunwald, Hila Sharim, Tslil Gabrieli, Yael Michaeli, Dmitry Torchinsky, Matyas Juhasz, Kathryn R. Wagner, Jonathan Pevsner, Jeffrey G. Reifenberger, Alex R. Hastie, Han Cao, Elmar G. Weinhold, Yuval Ebenstein

The paper introduces R2OM2, a method combining optical methylation profiling with genome mapping to analyze epigenetic variation in single cells and large structural aberrations.

bioRxiv · Mar 6, 2017 · PreprintGenetics