Max F. K. Happel

Comparative analysis of primary auditory cortical responses in bats and mice to repetitive stimuli trains

This study compares auditory cortical responses in bats and mice to repetitive stimuli, finding better signal-to-noise ratio and response suppression in bats.

Inhibiting presynaptic calcium channel mobility in the auditory cortex suppresses synchronized input processing

The paper investigates how inhibiting presynaptic calcium channel mobility in the auditory cortex affects synchronized input processing and reveals its role in adjusting network activity across synaptic input strengths.

Acute and long-term circuit-level effects in the auditory cortex after sound trauma

This study investigates acute and long-term changes in auditory cortex circuitry after sound trauma in gerbils, showing compensatory mechanisms in thalamocortical and intracortical inputs.

Task rule and choice are reflected by layer-specific processing in rodent auditory cortical microcircuits

This study shows that different layers of the auditory cortex encode task-related and choice-related information during a behavioral task in rodents.

Removal of the extracellular matrix biases auditory cortical layer dynamics towards supragranular frequency integration

This study removes the extracellular matrix in auditory cortex and finds changes in synaptic activity patterns and frequency integration.

Ketamine anesthesia induces gain enhancement via recurrent excitation in granular input layers of the auditory cortex

This study shows ketamine increases recurrent excitation in granular layers of the auditory cortex, leading to gain enhancement in response to auditory stimuli.

Optogenetic stimulation of the VTA modulates a frequency-specific gain of thalamocortical inputs in infragranular layers of the auditory cortex

This study shows that optogenetic stimulation of the VTA enhances thalamic inputs to infragranular layers of the auditory cortex, leading to frequency-specific gain amplification and prolonged sensory processing effects.

Dopamine modulates the integrity of the perisynaptic extracellular matrix at excitatory synapses

This study shows dopamine modulates ECM integrity at excitatory synapses via D1 receptors and proteases ADAMTS-4/5, affecting brevican and aggrecan cleavage.