François Lecointe

A Pair of DNA Glucosyltransferases Elevate Counter-defense in Bacteriophage T4

This study shows that bacteriophage T4 uses two glucosyltransferases to modify its DNA, helping it evade bacterial defense systems, with redundancy providing an evolutionary advantage.

Atypical Replication Error Pattern and Limited Repair Efficiency Contribute to Elevated Mutation Rate in Phage lambda

This study measures the mutation rate of phage lambda and finds it is higher than its host E. coli but not significantly increased by MMR inactivation.

T7 DNA polymerase treatment improves quantitative sequencing of both double-stranded and single-stranded DNA viruses

The paper compares DNA preparation methods for virome sequencing, finding that T7 DNA polymerase treatment improves representation of both ssDNA and dsDNA viruses compared to MDA or xGen kit.