Development in context: interferon response networks regulate human fetal thymic epithelial cell differentiation
Abdulvasey Mohammed, Benjamin D. Solomon, Priscila Ferreira Slepicka, Kelsea M. Hubka, Hanh Dan Nguyen, Wenqing Wang, Martin Arreola, Michael Chavez, Christine Y. Yeh, Doo Kyung Kim, Virginia D. Winn, Casey A. Gifford, Veronika R. Kedlian, Jong-Eun Park, Georg A. Holländer, , Katja Gabriele Weinacht
This study uses single-cell transcriptomics to identify gene regulatory networks and lineage trajectories in human fetal thymic epithelial cells, revealing interferon response pathways that distinguish thymic epithelium from other anterior foregut-derived organs.
bioRxiv · Oct 2, 2022 · PreprintDevelopmental Biology