Chromatin context-dependent deacetylation by the asymmetric Rpd3L
Hongyun Zhao, Huadong Li, Chi Wang, Xuechen Yang, He Li, Binqian Zou, Shuqi Dong, Nan Zhang, Yuxing Zhou, Li Yi, Ying Zhang, Yixuan Xie, Dajiang Qin, William Chong Hang Chao, Duanqing Pei, Jun He
This study reveals how the Rpd3L complex uses an asymmetric architecture to activate deacetylation in response to chromatin context.
Nucleic Acids Research · Apr 28, 2026Peer-reviewedMolecular Biology