Mitochondrial Raf1 Regulates Glutamine Catabolism
Ronald L. Shanderson, Ian D. Ferguson, Luca Ducoli, Weili Miao, Suhas Srinivasan, Zurab Siprashvili, Albert M. Li, Mary Grace Velasco, Yang Li, Christine N. Hoang, Jiangbin Ye, Paul A. Khavari
This paper identifies Raf1 within mitochondria where it interacts with GLS to regulate glutamine catabolism and tumorigenesis, independent of MAPK signaling.
bioRxiv · Mar 8, 2024Cancer Biology