Yang Zhao

The paper studies how dietary metabolites interact with genetic variants to influence colon cancer risk through transcriptional regulation.

This study shows that Xist ribonucleoprotein complexes drive sex-biased autoimmunity in males, leading to autoimmune pathology and reprogramming of immune cells to resemble female patterns.

This study shows glucose acts as a morphogen that modulates transcription factor dimerization during tissue differentiation.

The paper examines dynamic chromatin changes in human CAR T cells during exhaustion, identifying regulatory networks and enhancer roles in exhaustion-associated genes.

This study shows that TERT inactivation accelerates stem cell differentiation and disrupts clone formation, independent of telomere elongation, and links TERT to MYC activity.

The paper demonstrates that the XIST RNA-protein complex has a modular architecture that determines RBP binding and m6A modification, beyond sequence motifs.

The paper identifies lnc-NR2F1 as a pro-neurogenic lncRNA mutated in neurodevelopmental disorders through genetic and functional studies.