Margaret G. Guo

The paper identifies disease-linked regulatory DNA variants and their impact on epidermal homeostasis by analyzing SNVs, TF binding, and gene dysregulation in polygenic skin diseases.

This study shows glucose acts as a morphogen that modulates transcription factor dimerization during tissue differentiation.

This paper develops a knowledge graph embedding method to identify drug repurposing opportunities for rare diseases by integrating biomedical literature and validating hypotheses through external sources.

The paper uses gene expression data and network-based methods to improve psychiatric disease diagnosis and drug treatment prioritization.