Quan Le

ProNotch converts extracellular protease activity into programmable transcriptional outputs by using a modular receptor system that responds to protease cleavage.

This paper introduces a superresolution microscopy technique called centroid reassignment microscopy (CRM) that enables fast, robust, and protocol-compatible imaging of live samples.

The paper introduces protease-containing nanobodies controlled by antiviral drugs to manipulate intracellular protein-protein interactions.