Michael B. Orger

Sardine: a modular framework for developing data acquisition and near real-time analysis applications

Sardine provides a modular framework for controlling experimental setups and enabling real-time data analysis through dynamic module networks.

Characterisation of transgenic lines labelling reticulospinal neurons in larval zebrafish

The paper characterizes four existing and three new transgenic lines in larval zebrafish to label reticulospinal neurons and other brainstem neurons, providing genetic access for functional studies.

Neural microexons modulate arousal states via cAMP signalling in zebrafish

This study shows that srrm3 regulates arousal states in zebrafish via cAMP signaling, with mutations causing hyperarousal and transcriptional changes.

Uncovering multiscale structure in the variability of larval zebrafish navigation

The paper develops a method to analyze behavioral variability in larval zebrafish by identifying motor strategies and their transitions across different environmental cues.

Megabouts: a flexible pipeline for zebrafish locomotion analysis

Megabouts is a software package for zebrafish locomotion analysis that uses a Transformer neural network to classify behaviors flexibly across tracking methods and frame rates.

The Adaptor Protein 2 (AP2) complex modulates habituation and behavioral selection across multiple pathways and time windows

This study shows the AP2 complex regulates habituation and behavioral selection in zebrafish, with ap2s1 playing a key role in modulating escape behavior across different sensory contexts and time windows.

Neutrophil immune profile controls spinal cord regeneration in zebrafish

The paper shows that neutrophil immune profile influences spinal cord regeneration in zebrafish by modulating inflammation resolution and macrophage/microglia presence.

Structural and functional organization of visual responses in the inferior olive of larval zebrafish

The paper investigates sensory representations in the inferior olive of larval zebrafish, finding spatial and functional organization of visual responses in IO neurons.

Dimensionality reduction reveals separate translation and rotation populations in the zebrafish hindbrain

The paper uses dimensionality reduction to identify distinct populations of neuronal activity in the zebrafish hindbrain associated with translation and rotation behaviors.

Early-life social experience shapes social avoidance reactions in larval zebrafish

This study shows that early-life social isolation in larval zebrafish increases social avoidance behaviors, mediated by the lateral line sensory system.

A retinal circuit generating a dynamic predictive code for orientated features

The paper investigates how retinal circuits implement dynamic predictive coding for oriented features through synaptic tuning and inhibition.

Clusterdv, a simple density-based clustering method that is robust, general and automatic.

Clusterdv is a density-based clustering method that automatically determines cluster number and distribution without manual parameter adjustment, performing well on synthetic and experimental data.