Elizabeth A. Ostrowski

A comprehensive assessment of tandem repeat genotyping methods for Nanopore long-read genomes

This paper benchmarks 7 TR genotyping tools using Nanopore long-read data, finding that no single tool is best across all metrics, and that sequence-level accuracy is crucial for clinical and population studies.

Hypermutable hotspot enables the rapid evolution of self/non-self recognition genes in Dictyostelium

The paper investigates the rapid evolution of self/non-self recognition genes in Dictyostelium by analyzing genome sequences and identifying a hypermutable hotspot in the tgrBC locus.

Evolutionary dynamics of the tgr gene family in Dictyostelium allows escape from Crozier's Paradox

The paper examines Crozier's Paradox in Dictyostelium discoideum by analyzing tgrB1 and tgrC1 genes, finding no strong evidence for the paradox and suggesting recombination generates genetic variation.

Natural variation in fruiting body morphology in the amoeba Dictyostelium discoideum

The paper examines variation in fruiting body morphology and stalk investment in natural populations of Dictyostelium discoideum, finding differences in altruism investment across populations and scales.

Dominance hierarchies are linear but shallow in the social amoeba Dictyostelium discoideum.

The paper examines dominance hierarchies in Dictyostelium discoideum, finding they are linear but shallow in co-occurring strains, suggesting competitive equivalence at local scales.

Discrimination of Gram-Positive versus Gram-Negative Bacteria by the Social Amoeba Dictyostelium discoideum

This study shows that Dictyostelium discoideum preferentially migrates toward Gram-negative bacteria over Gram-positive ones, mediated in part by cAMP sensing.