Abel Torres Espin

Polytraumatic SCI worsens maladaptive plasticity in spinal motor systems

This study investigates how polytraumatic spinal cord injury (SCI) combined with spared nerve injury (SNI) exacerbates maladaptive plasticity in spinal motor systems through increased GluA1 expression and AMPAR currents.

Conditioning electrical stimulation enhances functional rewiring in a mouse model of nerve transfer to treat chronic spinal cord injury

A Kinematic Deviation Index (KDI) for Evaluation of Forelimb Function in Rodents

The paper introduces a kinematic deviation index (KDI) to assess forelimb function in rodents, demonstrating its ability to detect movement differences and response to interventions.

Improving rigor and reproducibility in western blot experiments with the blotRig analysis software

The paper describes best practices for western blot experiments and introduces blotRig, a tool to improve rigor and reproducibility in quantitative analysis.

Sexually dimorphic differences in angiogenesis markers predict brain aging trajectories

The paper examines associations between circulating angiogenesis markers and brain aging trajectories in humans, finding sex-specific effects and implications for vascular cognitive impairment.

Expert-integrated automated machine learning uncovers hemodynamic predictors in spinal cord injury

This paper develops an AutoML framework with explainable AI tools to identify hemodynamic predictors of spinal cord injury outcomes.

Open Data Commons for Preclinical Traumatic Brain Injury Research: Empowering Data Sharing and Big Data Analytics

The paper introduces ODC-TBI, a platform for sharing preclinical TBI data, enabling big data analytics and machine learning to address heterogeneity in TBI research.

Blood RNA Profiles are Diagnostic for Severity in Human Acute Spinal Cord Injury

The paper identifies 197 genes in peripheral blood cells whose expression correlates with acute spinal cord injury severity, achieving 72.7% accuracy in predicting injury grades.