Author

Jackie L. Shane

University of PittsburghORCID 0000-0002-9796-7765Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:C. elegans· 1 Organism:mouse· 1

Frequent Co-Authors

Anthony J. St. LegeriD· 2 shared Yannis RigasiD· 2 shared Akriti GuptaiD· 1 shared Amy Zhang· 1 shared Benjamin H. SchwarziD· 1 shared Benjamin R. TreatiD· 1 shared Biying XuiD· 1 shared Crystal L. RichardsiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMicrobiology

Anthony J. St. LegerORCID

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2 papers

Recent·Most cited

C. mastitidis requires the protein Sortase F to colonize the eye

Yannis Rigas, Jackie L. Shane, Benjamin R. Treat, Robert M. Q. Shanks, Anthony J. St. Leger

This study identifies Sortase F as essential for Corynebacterium mastitidis to colonize the eye and induce immune responses.

bioRxiv · Mar 12, 2026 · PreprintMicrobiology

Commensal-derived Trehalose Monocorynomycolate Triggers γδ T Cell-driven Protective Ocular Barrier Immunity

Xiaoyan Xu, Yannis Rigas, Mary Joseph Mattapallil, Jing Guo, Keiko Sakamoto, Keisuke Nagao, Vijayaraj Nagarajan, Eric Bohrnsen, Crystal L. Richards, Akriti Gupta, Guillaume Gaud, Paul E. Love, Timothy Jiang, Amy Zhang, Biying Xu, , Rachel R Caspi

This paper identifies trehalose monocorynomycolate (TMCM) from C. mast as a stimulator of IL-17-producing γδ T cells at the ocular surface, which protects against corneal infection.

Immunity · Jan 19, 2026Peer-reviewedImmunology