Cardiovascular disease causes proinflammatory microvascular changes in the human right atrium
Suvi Linna-Kuosmanen, Eloi Schmauch, Kyriaki Galani, Johannes Ojanen, Carles A. Boix, Tiit Örd, Anu Toropainen, Prosanta Singha, Pierre R. Moreau, Kristiina Harju, Adriana Blazeski, Åsa Segerstolpe, Veikko Lahtinen, Lei Hou, Kai Kang, , M Kellis
The paper uses single-nuclei RNA-seq and spatial transcriptomics to analyze gene expression changes in the right atrium of patients with ischemic heart disease, revealing inflammatory microvascular dysfunction and altered tissue composition.
Cell Reports Medicine · May 1, 2024Peer-reviewedMolecular Biology