Elamaran Meibalan

Severe malarial anaemia is associated with parasite enrichment and host alterations in the bone marrow

This study shows that severe malarial anaemia is linked to increased red blood cell production, iron metabolism, tissue injury, and parasite biomass in bone marrow, with better resolution from bone marrow analysis than peripheral blood.

Immune disease dialogue of chemokine-based cell communications as revealed by single-cell RNA sequencing meta-analysis

The paper performs a meta-analysis of scRNA-seq data to identify disease-specific and shared chemokine-based cell communication patterns in immune diseases.

Cardiovascular disease causes proinflammatory microvascular changes in the human right atrium

The paper uses single-nuclei RNA-seq and spatial transcriptomics to analyze gene expression changes in the right atrium of patients with ischemic heart disease, revealing inflammatory microvascular dysfunction and altered tissue composition.